Description

Thiophene-2-Ol, 5-Nitro- (9Ci) is a high-purity nitro-substituted thiophene derivative, a key heterocyclic building block for advanced chemical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific electronic and steric properties into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to develop novel ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the nitro-thiophene core provides unique coloristic and stability properties.

Basic Information

Item	Details
Product Name	Thiophene-2-Ol, 5-Nitro- (9Ci)
CAS No.	550379-21-0
Molecular Formula	C4H3NO3S
Molecular Weight	145.14 g/mol
Synonyms	5-Nitrothiophen-2-ol; 2-Hydroxy-5-nitrothiophene; 5-Nitro-2-thiophenol; 5-Nitro-2-thienol; 5-Nitro-2-thiophenecarbinol; 5-Nitrothiophene-2-ol; 2-Thienol, 5-nitro-
EINECS	Contact for details

Quality Control

Our Thiophene-2-Ol, 5-Nitro- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.