Description

2-(3-Hydroxy-Phenyl)-3H-Benzoimidazole-5-Carboxylic Acid is a high-purity, functionalized benzimidazole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating molecules with targeted biological or photophysical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, or plant growth regulators that leverage the benzimidazole core's bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a functional moiety in the design of electron-transport or emissive materials for display and lighting technologies.
• Coordination Chemistry & Catalysis: Serves as a chelating ligand for metal complexes used in catalytic processes or as molecular sensors.
• Polymer & Material Science: Incorporated into polymer backbones or as a side-chain modifier to impart specific thermal, mechanical, or optical properties.
• Bioconjugation & Probe Development: Utilized in the creation of fluorescent probes or biochemical tools for diagnostic and research applications.

Basic Information

Product Name	2-(3-Hydroxy-Phenyl)-3H-Benzoimidazole-5-Carboxylic Acid
CAS No.	550300-30-6
Molecular Formula	C14H10N2O3
Molecular Weight	254.24 g/mol
Synonyms	2-(3-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid; 5-Carboxy-2-(3-hydroxyphenyl)benzimidazole; 1H-Benzimidazole-5-carboxylic acid, 2-(3-hydroxyphenyl)-; Benzimidazole-5-carboxylic acid, 2-(3-hydroxyphenyl)-; 2-(3-Hydroxy-phenyl)-3H-benzoimidazole-5-carboxylic acid; 550300-30-6; 2-(m-Hydroxyphenyl)-5-benzimidazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxy-Phenyl)-3H-Benzoimidazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.