Description

3-(4-Fluorophenyl)-7-Hydroxy-2H-Chromen-2-One is a specialized fluorinated coumarin derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmaceuticals and functional materials, offering a unique scaffold for further chemical modification. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and fluorescent probes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the coumarin core.
• Fluorescent Probe Synthesis: Acts as a starting material for creating sensitive fluorescent dyes and sensors used in biochemical assays and diagnostics.
• Material Science: Employed in the research of organic light-emitting diodes (OLEDs) and other advanced organic electronic materials.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical reactions.
• Fine Chemical Synthesis: A building block for synthesizing more complex, value-added specialty chemicals with specific optical or biological properties.

Basic Information

Product Name	3-(4-Fluorophenyl)-7-Hydroxy-2H-Chromen-2-One
CAS No.	549501-15-7
Molecular Formula	C15H9FO3
Molecular Weight	256.23 g/mol
Synonyms	7-Hydroxy-3-(4-fluorophenyl)coumarin; 3-(p-Fluorophenyl)-7-hydroxycoumarin; 7-Hydroxy-3-(4-fluorophenyl)-2H-chromen-2-one; 3-(4-Fluorophenyl)-7-hydroxychromen-2-one; 549501-15-7; 4-Fluorophenyl-7-hydroxycoumarin; 7-Hydroxy-3-(4'-fluorophenyl)coumarin
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-7-Hydroxy-2H-Chromen-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.