Description

Fexofenadine-D6 is a deuterium-labeled analog of the active pharmaceutical ingredient fexofenadine, specifically designed for use as an internal standard in analytical chemistry. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and quality control departments for method development, pharmacokinetic studies, and bioanalytical testing.

Application

• Internal Standard for LC-MS/MS: Serves as a critical internal standard for the precise quantification of fexofenadine in biological matrices (plasma, serum, urine) during bioanalytical method development and validation.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking and measurement of fexofenadine levels in drug metabolism and pharmacokinetic (DMPK) research.
• Pharmaceutical Quality Control: Used in analytical laboratories for assay development and impurity profiling of fexofenadine hydrochloride active pharmaceutical ingredient (API) and finished dosage forms.
• Clinical Research: Supports clinical trial studies requiring high-precision measurement of fexofenadine concentration for bioavailability and bioequivalence assessments.
• Forensic and Toxicological Analysis: Aids in the accurate detection and quantification of fexofenadine in forensic science and toxicology reports.

Basic Information

Product Name	Fexofenadine-D6
CAS No.	548783-71-7
Molecular Formula	C32H33D6NO4
Molecular Weight	516.69 g/mol
Synonyms	Fexofenadine-d6; (±)-4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethylbenzeneacetic Acid-d6; 2-[4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl]-2-methylpropanoic Acid-d6; Carboxyterfenadine-d6; Terfenadine Carboxylate-d6; Allegra-d6; Telfast-d6
EINECS	Contact for details

Quality Control

Our Fexofenadine-D6 is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment, chemical purity (by HPLC), and identification (by NMR and MS). We adhere to cGMP guidelines for the production of reference standards, ensuring traceability and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.