Description

N,n-Diethyl-2-(Trimethylsilyl)Indole-1-Carboxamide is a specialized organosilicon derivative of indole, serving as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxamide and a trimethylsilyl protecting group, makes it a critical building block for constructing complex heterocyclic frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole scaffold for biological activity.
• Material Science: Building block for creating functionalized organic semiconductors and advanced polymeric materials.
• Academic & R&D: Essential reagent in methodological studies for new C-H functionalization and cross-coupling reactions.
• Fine Chemical Synthesis: Intermediate for producing complex, high-value specialty chemicals used in flavors, fragrances, and dyes.

Basic Information

Product Name	N,n-Diethyl-2-(Trimethylsilyl)Indole-1-Carboxamide
CAS No.	548775-58-2
Molecular Formula	C₁₆H₂₄N₂OSi
Molecular Weight	288.46 g/mol
Synonyms	1-[(Diethylamino)carbonyl]-2-(trimethylsilyl)-1H-indole; 2-(Trimethylsilyl)-N,N-diethyl-1H-indole-1-carboxamide; N,N-Diethyl-2-trimethylsilylindole-1-carboxamide; 2-TMS-Indole-1-Carboxamide, N,N-Diethyl-; Diethyl(2-trimethylsilyl-1H-indol-1-yl)methanone; 548775-58-2; N,N-Diethyl-2-(trimethylsilyl)-1H-indole-1-carboxamide
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-2-(Trimethylsilyl)Indole-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.