Description

(5-Chlorothiophen-2-Yl)Methanamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is of significant commercial importance due to its role as a versatile synthon in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiophene and chlorinated heterocycle.
• Organic Synthesis Reagent: Serves as a versatile amine component in amide coupling reactions, reductive amination, and the preparation of urea and sulfonamide derivatives.
• Material Science Precursor: Employed in the research and development of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(5-Chlorothiophen-2-Yl)Methanamine Hydrochloride
CAS No.	548772-41-4
Molecular Formula	C5H7Cl2NS
Molecular Weight	184.09 g/mol
Synonyms	1-(5-Chlorothiophen-2-yl)methanamine hydrochloride; (5-Chloro-2-thienyl)methanamine hydrochloride; 2-Thiophenemethanamine, 5-chloro-, hydrochloride; 5-Chlorothiophene-2-methanamine hydrochloride; 2-(Aminomethyl)-5-chlorothiophene hydrochloride; 5-Chloro-2-thiophenemethylamine hydrochloride; (5-Chloro-2-thienylmethyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Chlorothiophen-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.