Description

1H-Indole, 7-Fluoro-4-Nitro- CAS NO 548458-05-5 is a high-purity, fluorinated nitroindole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which enables the introduction of both fluorine and nitro functional groups into complex heterocyclic frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the indole scaffold's prevalence in bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials with tailored optoelectronic properties.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical research to study enzyme mechanisms or protein interactions.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university laboratories and contract research organizations (CROs).

Basic Information

Product Name	1H-Indole, 7-Fluoro-4-Nitro-
CAS No.	548458-05-5
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	7-Fluoro-4-nitro-1H-indole; 4-Nitro-7-fluoroindole; 7-Fluoro-4-nitroindole; 1H-Indole-7-fluoro-4-nitro; 7-Fluoro-4-nitro-1H-indole; 4-Nitro-7-fluoro-1H-indole; 7-Fluoro-4-nitroindole; 548458-05-5
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole, 7-Fluoro-4-Nitro- is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible research and scale-up processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon when not in use to maintain purity and stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.