Description

4-(4-Bromophenyl)-2-(2-Cyano-Acetylamino)-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile molecular scaffold for constructing complex pharmacophores and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel thiophene-based drug candidates, particularly for kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its bromophenyl and cyanoacetamide functionalities.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic semiconductors for electronic applications.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry due to its reactive amine and ester groups.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific molecular library construction.

Basic Information

Item	Details
Product Name	4-(4-Bromophenyl)-2-(2-Cyano-Acetylamino)-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	546064-73-7
Molecular Formula	C16H13BrN2O3S
Molecular Weight	393.26 g/mol
Synonyms	Ethyl 4-(4-bromophenyl)-2-[(2-cyanoacetyl)amino]-3-thiophenecarboxylate; 4-(4-Bromophenyl)-2-[(cyanoacetyl)amino]-3-thiophenecarboxylic acid ethyl ester; 2-[(2-Cyanoacetyl)amino]-4-(4-bromophenyl)thiophene-3-carboxylic acid ethyl ester; 546064-73-7; AKOS BRN-0717; BRN 0717; CS-0136223; STK387561
EINECS	Contact for details

Quality Control

Our 4-(4-Bromophenyl)-2-(2-Cyano-Acetylamino)-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.