Description

Methyl 4-(4-Bromophenyl)-2-[(Cyanoacetyl)Amino]Thiophene-3-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for research and development in pharmaceutical and agrochemical discovery, serving as a key precursor for creating novel active molecules. It is primarily utilized by medicinal chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the discovery and synthesis of novel pesticides and herbicides, leveraging its bromophenyl and thiophene motifs.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic semiconductors and non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized in the development of fluorescent tags or activity-based probes for studying biological processes.
• Academic & Contract Research: Essential for methodology development and novel reaction pathway exploration in university and CRO laboratories.
• Custom Synthesis & Scale-up: A starting material for contract manufacturing organizations (CMOs) engaged in producing bespoke fine chemicals for client projects.

Basic Information

Product Name	Methyl 4-(4-Bromophenyl)-2-[(Cyanoacetyl)Amino]Thiophene-3-Carboxylate
CAS No.	545385-40-8
Molecular Formula	C15H11BrN2O3S
Molecular Weight	379.23 g/mol
Synonyms	Methyl 2-[(cyanoacetyl)amino]-4-(4-bromophenyl)thiophene-3-carboxylate; 4-(4-Bromophenyl)-2-[(cyanoacetyl)amino]thiophene-3-carboxylic acid methyl ester; 2-[(1-Cyano-1-oxo-2-aminoethyl)amino]-4-(4-bromophenyl)thiophene-3-carboxylic acid methyl ester; Thiophene-3-carboxylic acid, 4-(4-bromophenyl)-2-[(cyanoacetyl)amino]-, methyl ester; CAS 545385-40-8
EINECS	Contact for details

Quality Control

Our Methyl 4-(4-Bromophenyl)-2-[(Cyanoacetyl)Amino]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.