Description

tert-Butyl Octahydro-4-Hydroxyindole-1-Carboxylate is a high-purity, protected indoline derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of biologically active molecules, including potential drug candidates targeting neurological and cardiovascular diseases.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its complex, functionalized ring system.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring high stereochemical purity.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic chemistry, particularly in stereoselective synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	tert-Butyl Octahydro-4-Hydroxyindole-1-Carboxylate
CAS No.	543910-49-2
Molecular Formula	C₁₃H₂₃NO₃
Molecular Weight	241.33 g/mol
Synonyms	1-Boc-4-hydroxyindoline; 1-(tert-Butoxycarbonyl)-4-hydroxyindoline; 4-Hydroxyindoline-1-carboxylic acid tert-butyl ester; tert-Butyl 4-hydroxy-2,3-dihydro-1H-indole-1-carboxylate; 1-N-Boc-4-hydroxyindoline; (4-Hydroxy-2,3-dihydro-1H-indol-1-yl)(tert-butoxy)methanone; Boc-4-hydroxyindoline
EINECS	Contact for details

Quality Control

Our tert-Butyl Octahydro-4-Hydroxyindole-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.