Description

tert-Butyl 4-Oxo-Octahydroindole-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its bicyclic indoline core. This compound matters as a critical building block for the synthesis of complex molecules, offering a protected amine and a ketone functionality for further derivatization. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing indoline-based scaffolds and exploring structure-activity relationships (SAR).
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for method development and novel compound libraries.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a protected, stereochemically defined indoline structure.

Basic Information

Product Name	tert-Butyl 4-Oxo-Octahydroindole-1-Carboxylate
CAS No.	543910-34-5
Molecular Formula	C₁₃H₂₁NO₃
Molecular Weight	239.31 g/mol
Synonyms	1-Boc-4-oxo-octahydroindole; tert-Butyl 4-oxo-2,3,3a,4,5,6,7,7a-octahydro-1H-indole-1-carboxylate; 4-Oxo-1-(tert-butoxycarbonyl)octahydroindole; 1-N-Boc-4-oxo-octahydroindole; Octahydro-4-oxo-1H-indole-1-carboxylic acid tert-butyl ester; 543910-34-5; Boc-4-oxo-octahydroindole
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Oxo-Octahydroindole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.