Description

4-(3-Bromophenyl)-6,8-Dichloro-2-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetically derived organic compound that serves as a critical advanced intermediate in modern chemical synthesis. Its complex heterocyclic structure, featuring bromophenyl and dichloro substituents, makes it a valuable building block for constructing more complex molecules with specific pharmacological or material science properties. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in medicinal chemistry, agrochemical research, and the synthesis of novel fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets or other therapeutic areas requiring complex nitrogen-containing heterocycles.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block in the development of novel herbicides, fungicides, or insecticides, leveraging its halogenated aromatic system.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and complex organic materials.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting synthetic organic chemistry and methodological studies.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-(3-Bromophenyl)-6,8-Dichloro-2-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	543739-81-7
Molecular Formula	C₁₇H₁₅BrCl₂N • HCl
Molecular Weight	437.58 g/mol
Synonyms	4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 4-(3-Bromophenyl)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinoline hydrochloride; 6,8-Dichloro-2-methyl-4-(3-bromophenyl)-1,2,3,4-tetrahydroisoquinoline HCl; 543739-81-7; Tetrahydroisoquinoline derivative, bromophenyl dichloro methyl hydrochloride salt
EINECS	Contact for details

Quality Control

Our production of 4-(3-Bromophenyl)-6,8-Dichloro-2-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.