Description

4-(3-Bromophenyl)-6,8-Dichloro-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the development of new therapeutic agents.

Application

This specialized intermediate serves as a critical building block in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Key precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and safety profiles.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Contract Manufacturing: Essential raw material for custom synthesis and scale-up services provided to the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	4-(3-Bromophenyl)-6,8-Dichloro-2-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	543737-10-6
Molecular Formula	C16H14BrCl2N
Molecular Weight	371.10 g/mol
Synonyms	4-(3-Bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline; 6,8-Dichloro-2-methyl-4-(3-bromophenyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,8-dichloro-2-methyl-4-(3-bromophenyl)isoquinoline; 543737-10-6; AI3-52410; SCHEMBL218422; ZINC000257630911
EINECS	Contact for details

Quality Control

Our 4-(3-Bromophenyl)-6,8-Dichloro-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.