Description

1H-Pyrrolizine-1,2-Diol,Hexahydro-,(1R,2R,7Ar)-(9Ci) is a high-purity, stereochemically defined chiral compound, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in enabling the construction of complex molecular architectures with precise stereochemical control, which is paramount for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds. This product is essential for research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable access to high-quality, structurally complex building blocks.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of potential drug candidates, particularly in classes targeting neurological or metabolic pathways.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development of new stereoselective catalytic reactions.
• Agrochemical Synthesis: Serves as a building block for creating novel, enantiomerically pure active ingredients for crop protection products.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Academic & Institutional R&D: A valuable tool for universities and research institutes studying pyrrolizidine alkaloid chemistry, natural product synthesis, and medicinal chemistry.
• Process Chemistry Development: Used to scale up and optimize synthetic routes for the commercial production of chiral target molecules.

Basic Information

Product Name	1H-Pyrrolizine-1,2-Diol,Hexahydro-,(1R,2R,7Ar)-(9Ci)
CAS No.	543690-37-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1R,2R,7aR)-Hexahydro-1H-pyrrolizine-1,2-diol; (1R,2R,7aR)-Octahydropyrrolo[1,2-a]pyrazine-1,2-diol; Hexahydro-1H-pyrrolizine-1,2-diol, (1R,2R,7aR)-; (1R,2R,7aR)-1,2-Dihydroxyhexahydro-1H-pyrrolizine; Chiral pyrrolizidine diol; (1R,2R,7aR)-HHP diol
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolizine-1,2-Diol,Hexahydro-,(1R,2R,7Ar)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment supports compliance in cGMP and ISO-guided environments for pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.