Description

(1E)-N'-Hydroxy-3-(2-Methyl-1H-Benzimidazol-1-Yl)Propanimidamide is a specialized benzimidazole derivative with a hydroxamic acid-like functional group, making it a valuable chemical intermediate for advanced synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the design of enzyme inhibitors and novel pharmacophores. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers for creating new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting metalloenzymes.
• Medicinal Chemistry Research: Used as a core scaffold for developing novel protease or histone deacetylase (HDAC) inhibitors.
• Agrochemical Development: Serves as a precursor in creating new fungicides or plant growth regulators with specific mode-of-action.
• Biochemical Probe Synthesis: Utilized to develop chemical tools for studying biological pathways and enzyme functions in vitro.
• Fine Chemical Synthesis: Intermediate for producing complex, high-value specialty chemicals used in various industrial research applications.

Basic Information

Product Name	(1E)-N'-Hydroxy-3-(2-Methyl-1H-Benzimidazol-1-Yl)Propanimidamide
CAS No.	537696-12-1
Molecular Formula	C12H14N4O
Molecular Weight	230.27 g/mol
Synonyms	N-Hydroxy-3-(2-methyl-1H-benzimidazol-1-yl)propanimidamide; 3-(2-Methyl-1H-benzimidazol-1-yl)-N-hydroxypropanimidamide; (E)-N'-Hydroxy-3-(2-methyl-1H-benzo[d]imidazol-1-yl)propanimidamide; 1H-Benzimidazole-1-propanimidamide, N-hydroxy-3-(2-methyl-1H-benzimidazol-1-yl)-, (1E)-; Propanimidamide, N-hydroxy-3-(2-methyl-1H-benzimidazol-1-yl)-, (1E)-; 537696-12-1; (1E)-N'-Hydroxy-3-(2-methyl-1H-benzoimidazol-1-yl)propanimidamide
EINECS	Contact for details

Quality Control

Every batch of (1E)-N'-Hydroxy-3-(2-Methyl-1H-Benzimidazol-1-Yl)Propanimidamide is manufactured and analyzed under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.