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1-(2-Chlorophenyl)-3-(4-Methoxyphenyl)Tetrahydro-1H-Thieno[3,4-D]Imidazol-2(3H)-One 5,5-Dioxide CAS NO 537680-83-4
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CAS No.:537680-83-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(2-Chlorophenyl)-3-(4-Methoxyphenyl)Tetrahydro-1H-Thieno[3,4-D]Imidazol-2(3H)-One 5,5-Dioxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly in the areas of central nervous system (CNS) and metabolic disorder research.
Application
- Pharmaceutical Intermediate: A key building block in the multi-step synthesis of proprietary drug candidates and novel APIs.
- Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
- Preclinical Studies: Serves as a critical material for producing compounds used in pharmacological and toxicological evaluations.
- Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
- Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and heterocyclic chemistry.
Basic Information
| Product Name | 1-(2-Chlorophenyl)-3-(4-Methoxyphenyl)Tetrahydro-1H-Thieno[3,4-D]Imidazol-2(3H)-One 5,5-Dioxide |
| CAS No. | 537680-83-4 |
| Molecular Formula | C20H17ClN2O4S |
| Molecular Weight | 416.88 g/mol |
| Synonyms | 1-(2-Chlorophenyl)-3-(4-methoxyphenyl)tetrahydrothieno[3,4-d]imidazol-2(3H)-one 5,5-dioxide; Tetrahydrothieno[3,4-d]imidazol-2(3H)-one, 1-(2-chlorophenyl)-3-(4-methoxyphenyl)-, 5,5-dioxide; 537680-83-4; Thieno[3,4-d]imidazol-2(3H)-one, 1-(2-chlorophenyl)-3-(4-methoxyphenyl)tetrahydro-, 5,5-dioxide; 1-(2-Chlorophenyl)-3-(4-methoxyphenyl)-1,3,3a,4,7,7a-hexahydro-2H-thieno[3,4-d]imidazol-2-one 5,5-dioxide |
| EINECS | Contact for details |
Quality Control
Our 1-(2-Chlorophenyl)-3-(4-Methoxyphenyl)Tetrahydro-1H-Thieno[3,4-D]Imidazol-2(3H)-One 5,5-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical R&D use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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