Description

n-(3,3-Dimethyl-3,4-Dihydroisoquinolin-1-Yl)Leucine is a specialized leucine derivative featuring a fused dihydroisoquinoline moiety, making it a valuable synthetic intermediate for advanced organic chemistry. This compound is particularly significant for its role in the research and development of novel pharmaceutical agents and bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology Probe: Serves as a precursor for labeled compounds or molecular probes used in biochemical and cellular studies.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability, bioavailability, or receptor binding affinity.
• Catalyst Ligand Synthesis: Potential precursor for chiral ligands used in asymmetric catalysis.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development and novel compound library synthesis.

Basic Information

Product Name	n-(3,3-Dimethyl-3,4-Dihydroisoquinolin-1-Yl)Leucine
CAS No.	537049-20-0
Molecular Formula	C₁₇H₂₄N₂O₂
Molecular Weight	288.39 g/mol
Synonyms	1-(3,3-Dimethyl-3,4-dihydro-1-isoquinolinyl)-4-methyl-2-aminopentanoic acid; Leucine, N-(3,3-dimethyl-3,4-dihydro-1-isoquinolinyl)-; (S)-2-Amino-4-methyl-N-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)pentanamide; (S)-N-(3,3-Dimethyl-3,4-dihydroisoquinolin-1-yl)leucine; 537049-20-0; UNII-8R6Q6L8K1T
EINECS	Contact for details

Quality Control

Our n-(3,3-Dimethyl-3,4-Dihydroisoquinolin-1-Yl)Leucine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.