Description

1-(Chloromethyl)-3,4-Dihydroisoquinoline is a versatile and reactive heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the chloromethyl group, which provides a key handle for further functionalization, enabling the construction of complex molecular architectures. This intermediate is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive molecules, including potential central nervous system (CNS) agents and other therapeutic compounds.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a building block for creating novel nitrogen-containing ligands used in catalytic systems.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized isoquinoline scaffolds.

Basic Information

Product Name	1-(Chloromethyl)-3,4-Dihydroisoquinoline
CAS No.	537017-56-4
Molecular Formula	C10H10ClN
Molecular Weight	179.65 g/mol
Synonyms	1-(Chloromethyl)-1,2,3,4-tetrahydroisoquinoline; 3,4-Dihydro-1-(chloromethyl)isoquinoline; 1-(Chloromethyl)-3,4-dihydroisoquinoline; 1-Chloromethyl-3,4-dihydroisoquinoline; 1,2,3,4-Tetrahydro-1-(chloromethyl)isoquinoline; Isoquinoline, 1-(chloromethyl)-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-3,4-Dihydroisoquinoline is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.