Description

1H-Indole-2-Carboxylicacid,2,3,4,5,6,7-Hexahydro-,(2S)-(9Ci) is a chiral, saturated indole derivative that serves as a sophisticated building block in advanced organic synthesis. Its value lies in its stereochemically defined core structure, which is critical for imparting specific biological activity and selectivity in final compounds. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a chiral scaffold in the development of novel catalytic systems.
• Chemical Biology & Proteomics: Serves as a core structure for designing molecular probes and activity-based protein profiling (ABPP) agents.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,2,3,4,5,6,7-Hexahydro-,(2S)-(9Ci)
CAS No.	537014-85-0
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2S)-1,2,3,4,5,6,7-Heptahydroindole-2-carboxylic acid; (S)-Octahydroindole-2-carboxylic acid; (2S)-2,3,4,5,6,7-Hexahydro-1H-indole-2-carboxylic acid; (S)-Hexahydroindole-2-carboxylic acid; (S)-HICA; (S)-2-Carboxyhexahydroindole; (S)-Perhydroindole-2-carboxylic acid; (2S)-Octahydro-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Identity and purity are confirmed through a suite of analytical techniques including HPLC, chiral HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.