Description

1H-Indole-2-Carboxylic Acid, 2,3,5,6-Tetrahydro-5,6-Dioxo-, Methyl Ester, (2R)- (9Ci) is a high-purity, chiral synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its complex, functionalized indole-dione structure, which serves as a versatile building block for constructing pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Utilized in advanced organic reactions, including asymmetric synthesis and cyclization reactions, to create novel heterocyclic compounds.
• Agrochemical Research: Serves as a starting material for developing new agrochemicals with potential herbicidal or insecticidal activity.
• Material Science Research: Investigated for its potential use in creating specialized organic electronic materials or ligands for catalysis.
• Academic & R&D Laboratories: Used in methodological studies and for exploring new chemical spaces in medicinal chemistry programs.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 2,3,5,6-Tetrahydro-5,6-Dioxo-, Methyl Ester, (2R)- (9Ci)
CAS No.	535932-03-7
Molecular Formula	C11H9NO5
Molecular Weight	235.19 g/mol
Synonyms	(2R)-Methyl 5,6-dihydro-5,6-dioxo-1H-indole-2-carboxylate; (R)-Methyl 2,3,5,6-tetrahydro-5,6-dioxo-1H-indole-2-carboxylate; Methyl (2R)-2,3,5,6-tetrahydro-5,6-dioxo-1H-indole-2-carboxylate; (R)-1H-Indole-2-carboxylic acid, 2,3,5,6-tetrahydro-5,6-dioxo-, methyl ester; (2R)-1H-Indole-2-carboxylic acid, 2,3,5,6-tetrahydro-5,6-dioxo-, methyl ester; CAS 535932-03-7
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid, 2,3,5,6-Tetrahydro-5,6-Dioxo-, Methyl Ester, (2R)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.