Description

(Dtbm)2P(O)H is a specialized organophosphorus compound, specifically a secondary phosphine oxide, known for its utility as a versatile ligand and reagent in advanced chemical synthesis. Its value lies in its ability to facilitate challenging catalytic transformations and serve as a key building block for complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where precision and reliability are paramount.

Application

• Catalysis: As a ligand in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Negishi) for C-C and C-X bond formation.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators.
• Material Science: Precursor for functional polymers, flame retardants, and advanced organic electronic materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies.
• Coordination Chemistry: Used to prepare metal complexes with tailored properties for catalysis and material applications.

Basic Information

Product Name	(Dtbm)2P(O)H
CAS No.	535925-40-7
Molecular Formula	C18H39OP
Molecular Weight	302.48 g/mol
Synonyms	Di-tert-butylphosphine oxide; Bis(1,1-dimethylethyl)phosphine oxide; Di-tert-butylphosphinous acid; (Dtbm)2P(O)H; Di-t-butylphosphine oxide; DTBPO; DTBP-H; (t-Bu)2P(O)H
EINECS	Contact for details

Quality Control

Our (Dtbm)2P(O)H CAS NO 535925-40-7 is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.