Description

Methyl 3-Iodo-1H-Indole-2-Carboxylate is a high-purity, synthetically valuable halogenated indole derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block for organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced activity.
• Organic Synthesis Reagent: Used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a substrate for further functionalization to create diverse chemical libraries.
• Material Science: Intermediate in the synthesis of organic semiconductors, dyes, and photoactive materials for electronic applications.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and process development in academic and CRO/CMO settings.

Basic Information

Product Name	Methyl 3-Iodo-1H-Indole-2-Carboxylate
CAS No.	534595-85-2
Molecular Formula	C10H8INO2
Molecular Weight	301.08 g/mol
Synonyms	Methyl 3-iodoindole-2-carboxylate; 3-Iodo-1H-indole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 3-iodo-, methyl ester; Methyl 3-iodo-1H-indole-2-carboxylate; 2-Carbomethoxy-3-iodoindole; 3-Iodoindole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Iodo-1H-Indole-2-Carboxylate adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.