Description

2-Thiazoleacetonitrile, 4,5-Dihydro-5-Methyl-4-Oxo- (9Ci) is a specialized heterocyclic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex thiazole-containing scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the research and development of new drug candidates, particularly those targeting various enzyme families.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, and insecticides where the thiazole moiety imparts specific biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Academic & Contract Research: A valuable reagent for methodological studies and library synthesis in academic and contract research organizations (CROs).
• Fine Chemical Production: Integrated into multi-step synthetic routes for high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-Thiazoleacetonitrile, 4,5-Dihydro-5-Methyl-4-Oxo- (9Ci)
CAS No.	533885-52-8
Molecular Formula	C6H6N2OS
Molecular Weight	154.19 g/mol
Synonyms	4,5-Dihydro-5-methyl-4-oxo-2-thiazoleacetonitrile; 5-Methyl-4-oxo-4,5-dihydro-2-thiazoleacetonitrile; 2-(Cyanomethyl)-5-methyl-4,5-dihydrothiazol-4-one; (5-Methyl-4-oxo-4,5-dihydrothiazol-2-yl)acetonitrile; 4,5-Dihydro-5-methyl-4-oxothiazole-2-acetonitrile
EINECS	Contact for details

Quality Control

Our 2-Thiazoleacetonitrile, 4,5-Dihydro-5-Methyl-4-Oxo- (9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.