Description

[(1R,3S)-2,2-Dimethyl-3-(2-Methyl-1H-Indol-3-Yl)Cyclopropyl]Acetic Acid is a high-purity chiral cyclopropane derivative, a key synthetic intermediate prized for its complex stereochemistry. This compound is critical for ensuring the precise stereochemical integrity required in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of complex drug candidates, particularly in antiviral and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is essential for biological activity.
• Asymmetric Synthesis: Serves as a sophisticated synthon in academic and industrial research focused on stereoselective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of other high-value, specialty chemicals requiring the cyclopropane-indole structural motif.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	[(1R,3S)-2,2-Dimethyl-3-(2-Methyl-1H-Indol-3-Yl)Cyclopropyl]Acetic Acid
CAS No.	530100-19-7
Molecular Formula	C₁₇H₂₁NO₂
Molecular Weight	271.35 g/mol
Synonyms	(1R,3S)-2,2-Dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropane-1-acetic acid; (1R,3S)-3-(2-Methyl-1H-indol-3-yl)-2,2-dimethylcyclopropanecarboxylic acid; (1R,3S)-Dicyclopropaneacetic acid derivative; 2,2-Dimethyl-3-(2-methyl-1H-indol-3-yl)cyclopropylacetic acid (stereospecific); Chiral indole-cyclopropane carboxylic acid; Stereoisomer of Prallethrin acid intermediate; 530100-19-7 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our [(1R,3S)-2,2-Dimethyl-3-(2-Methyl-1H-Indol-3-Yl)Cyclopropyl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,3S)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.