Description

1-(3-Fluorobenzyl)-5-Bromo-1H-Indole-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated indole structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological processes and protein function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional labs for exploratory research in organic synthesis and drug discovery.

Basic Information

Product Name	1-(3-Fluorobenzyl)-5-Bromo-1H-Indole-3-Carbaldehyde
CAS No.	528887-87-8
Molecular Formula	C16H11BrFNO
Molecular Weight	332.17 g/mol
Synonyms	5-Bromo-1-[(3-fluorophenyl)methyl]-1H-indole-3-carboxaldehyde; 1-[(3-Fluorophenyl)methyl]-5-bromo-1H-indole-3-carbaldehyde; 5-Bromo-1-(3-fluorobenzyl)indole-3-carboxaldehyde; 1-(3-Fluorobenzyl)-5-bromoindole-3-carbaldehyde; 3-Formyl-5-bromo-1-(3-fluorobenzyl)indole; 528887-87-8; 5-Bromo-1-(3-fluorobenzyl)-1H-indole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorobenzyl)-5-Bromo-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.