Description

Methyl 1-Formylindoline-3-Carboxylate is a high-purity, versatile indoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both formyl and ester functional groups, makes it a valuable building block for constructing complex heterocyclic frameworks. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex indole and indoline-based drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indoline scaffold for biological activity.
• Material Science: Building block for creating organic semiconductors, dyes, and photochromic materials due to its conjugated system.
• Academic & R&D: Essential reagent for methodological studies in organic synthesis, including novel cyclization and cross-coupling reactions.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, flavors, and fragrances requiring specific chiral or structural motifs.

Basic Information

Product Name	Methyl 1-Formylindoline-3-Carboxylate
CAS No.	528861-99-6
Molecular Formula	C12H11NO3
Molecular Weight	217.22 g/mol
Synonyms	1-Formylindoline-3-carboxylic acid methyl ester; Methyl 1-formyl-2,3-dihydro-1H-indole-3-carboxylate; 3-Carbomethoxy-1-formylindoline; 1H-Indole-3-carboxylic acid, 2,3-dihydro-1-formyl-, methyl ester; MFIC
EINECS	Contact for details

Quality Control

Our Methyl 1-Formylindoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.