Description

2-Bromo-1-(5-Chloro-2-Methyl-Thiophen-3-Yl)-Ethanone is a high-purity, specialized bromoketone derivative that serves as a critical building block in advanced organic synthesis. Its unique thiophene-based structure makes it a valuable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated thiophene core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in proteomics and bio-conjugation studies due to its reactive bromoacetyl group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	2-Bromo-1-(5-Chloro-2-Methyl-Thiophen-3-Yl)-Ethanone
CAS No.	528604-96-8
Molecular Formula	C7H6BrClOS
Molecular Weight	253.54 g/mol
Synonyms	2-Bromo-1-(5-chloro-2-methyl-3-thienyl)ethanone; 2-Bromo-1-(5-chloro-2-methylthiophen-3-yl)ethan-1-one; 3-Acetyl-5-chloro-2-methylthiophene, 2-bromo derivative; 1-(5-Chloro-2-methyl-3-thienyl)-2-bromoethanone; 528604-96-8; Ethanone, 2-bromo-1-(5-chloro-2-methyl-3-thienyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5-Chloro-2-Methyl-Thiophen-3-Yl)-Ethanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods (NMR, IR, MS), and impurity profiles. We adhere to ISO 9001 quality management standards, and production can be aligned with cGMP requirements for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.