Description

3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(4-Methylphenyl)-,(1S,4S,5R)-(9Ci) is a high-purity, stereochemically defined bicyclic lactone compound of significant interest in advanced organic synthesis. This chiral building block is valued for its rigid, fused-ring structure which serves as a key intermediate in the development of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, agrochemicals, and specialty materials where precise stereochemistry is critical for function. CAS No. 528588-22-9.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the construction of novel pesticide and herbicide molecules, where its bicyclic framework can contribute to unique modes of action and selectivity.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for the synthesis of sophisticated chiral ligands used in enantioselective catalytic processes.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties derived from its strained ring system.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for complex natural product synthesis and chemical library generation.

Basic Information

Product Name	3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(4-Methylphenyl)-,(1S,4S,5R)-(9Ci)
CAS No.	528588-22-9
Molecular Formula	C14H16O2
Molecular Weight	216.28 g/mol
Synonyms	(1S,4S,5R)-4-Ethyl-1-(4-methylphenyl)-3-oxabicyclo[3.1.0]hexan-2-one; 4-Ethyl-1-p-tolyl-3-oxabicyclo[3.1.0]hexan-2-one, (1S,4S,5R)-; (1S,4S,5R)-4-Ethyl-1-(p-tolyl)-3-oxabicyclo[3.1.0]hexan-2-one; Bicyclic Lactone Derivative 528588-22-9; Chiral Bicyclic Lactone Intermediate; p-Tolyl-substituted Oxabicyclohexanone
EINECS	Contact for details

Quality Control

Our 3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(4-Methylphenyl)-,(1S,4S,5R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric purity and identity verification via spectroscopic methods. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.