Description

Methyl 1-(2-Bromophenyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant interest in modern organic synthesis. This compound serves as a critical building block for the development of novel therapeutic agents, particularly in central nervous system (CNS) research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole and tetrahydro-β-carboline alkaloid derivatives with potential pharmacological activity.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities, especially for neurological targets.
• Organic Synthesis Research: Used in academic and industrial laboratories for methodological development in heterocyclic chemistry, including palladium-catalyzed cross-coupling reactions.
• Building Block for Bioactive Molecules: Employed in constructing molecules with potential affinity for serotonin, dopamine, or other neurotransmitter receptors.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Methyl 1-(2-Bromophenyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate
CAS No.	528523-10-6
Molecular Formula	C19H17BrN2O2
Molecular Weight	385.26 g/mol
Synonyms	1-(2-Bromophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester; Methyl 1-(2-bromophenyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylate; 1-(2-Bromophenyl)-2,3,4,9-tetrahydro-3-pyrido[3,4-b]indolecarboxylic acid methyl ester; Tetrahydro-β-carboline derivative; Bromophenyl tetrahydro-β-carboline ester
EINECS	Contact for details

Quality Control

Our Methyl 1-(2-Bromophenyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or GMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.