Description

Pyrrolo[2,1-A]Isoquinolin-3(2H)-One, 1,5,6,10B-Tetrahydro-1,2-Dihydroxy-, (1S,2S,10Br)- (9Ci) is a high-purity, chiral organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a sophisticated key chiral building block and pharmacophore for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Asymmetric Synthesis: Used as a building block in stereoselective organic synthesis to construct complex molecular architectures with defined stereochemistry.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Potential use as a tool compound for probing biological pathways and enzyme interactions in biochemical assays.

Basic Information

Product Name	Pyrrolo[2,1-A]Isoquinolin-3(2H)-One, 1,5,6,10B-Tetrahydro-1,2-Dihydroxy-, (1S,2S,10Br)- (9Ci)
CAS No.	524950-88-7
Molecular Formula	C13H13NO3
Molecular Weight	231.25 g/mol
Synonyms	(1S,2S,10bR)-1,2-Dihydroxy-1,5,6,10b-tetrahydro-2H-pyrrolo[2,1-a]isoquinolin-3-one; (1S,2S,10bR)-1,2,5,6,10,10b-Hexahydro-1,2-dihydroxypyrrolo[2,1-a]isoquinolin-3-one; Pyrroloisoquinolinone derivative; Chiral pyrroloisoquinoline diol; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, chiral HPLC, 1H/13C NMR, and mass spectrometry to confirm identity, stereochemical purity, and chemical purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support cGMP standards for pharmaceutical applications, ensuring traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.