Description

Pyrrolo[2,1-A]Isoquinolin-3(2H)-One, 1,5,6,10B-Tetrahydro-1,2-Dihydroxy-, (1S,2S,10Bs)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This molecule serves as a critical chiral building block or synthetic intermediate for the development of complex pharmacologically active compounds. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, or infectious diseases.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce complex molecular architectures.
• Process Chemistry Development: Serves as a reference standard or an intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Academic & Institutional Research: Utilized in studies focusing on novel heterocyclic chemistry, natural product synthesis, or the development of new synthetic methodologies.

Basic Information

Product Name	Pyrrolo[2,1-A]Isoquinolin-3(2H)-One, 1,5,6,10B-Tetrahydro-1,2-Dihydroxy-, (1S,2S,10Bs)- (9Ci)
CAS No.	524950-87-6
Molecular Formula	C13H13NO3
Molecular Weight	231.25 g/mol
Synonyms	(1S,2S,10bS)-1,2-Dihydroxy-1,5,6,10b-tetrahydro-2H-pyrrolo[2,1-a]isoquinolin-3-one; (1S,2S,10bS)-1,5,6,10b-Tetrahydro-1,2-dihydroxypyrrolo[2,1-a]isoquinolin-3(2H)-one; 1,5,6,10b-Tetrahydro-1,2-dihydroxypyrrolo[2,1-a]isoquinolin-3(2H)-one, (1S,2S,10bS)-; Pyrrolo[2,1-a]isoquinoline-3(2H)-one, 1,5,6,10b-tetrahydro-1,2-dihydroxy-, (1S,2S,10bS)-; (1S,2S,10bS)-1,2-Dihydroxy-1,2,5,6,10,10b-hexahydropyrrolo[2,1-a]isoquinolin-3-one
EINECS	Contact for details

Quality Control

Our high-purity chiral intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.