Description

(2S,3E)-4-Bromo-1-(4-Fluorophenoxy)-3-Buten-2-Ol CAS NO 524714-06-5 is a high-purity chiral building block featuring a bromoalkene and a fluorinated aromatic ether moiety. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the synthesis of advanced, fluorinated agrochemicals and pesticides, leveraging the biological activity imparted by the fluorine atom.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers or precursors for specialty polymers and advanced materials.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, including cross-coupling reactions and stereoselective transformations.

Basic Information

Product Name	(2S,3E)-4-Bromo-1-(4-Fluorophenoxy)-3-Buten-2-Ol
CAS No.	524714-06-5
Molecular Formula	C10H10BrFO2
Molecular Weight	261.09 g/mol
Synonyms	(2S,3E)-4-Bromo-1-(4-fluorophenoxy)but-3-en-2-ol; 4-Bromo-1-(4-fluorophenoxy)-3-buten-2-ol, (2S,3E)-; (S,E)-4-Bromo-1-(4-fluorophenoxy)but-3-en-2-ol; (2S,3E)-4-Bromo-1-(p-fluorophenoxy)-3-buten-2-ol; CAS 524714-06-5; Bromofluorophenoxybutenol; Chiral Bromoalkene Intermediate
EINECS	Contact for details

Quality Control

Our (2S,3E)-4-Bromo-1-(4-Fluorophenoxy)-3-Buten-2-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity and impurity profile analysis via HPLC and GC. Certificates of Analysis (COA) detailing identity, assay, and purity are available for every batch and provided upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.