Description

3-({4-[(4-Methoxyphenyl)Sulfonyl]Piperazin-1-Yl}Methyl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonylpiperazine-indole hybrid structure. This compound is critical for medicinal chemistry research and development, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas such as central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and mechanisms of action.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Item	Detail
Product Name	3-({4-[(4-Methoxyphenyl)Sulfonyl]Piperazin-1-Yl}Methyl)-1H-Indole
CAS No.	524676-05-9
Molecular Formula	C21H25N3O3S
Molecular Weight	399.51 g/mol
Synonyms	1H-Indole, 3-[[4-[(4-methoxyphenyl)sulfonyl]-1-piperazinyl]methyl]-; 3-({4-[(4-Methoxyphenyl)Sulfonyl]Piperazin-1-Yl}Methyl)indole; 3-[[4-(4-Methoxyphenylsulfonyl)piperazin-1-yl]methyl]-1H-indole; 524676-05-9; 3-[(4-(4-Methoxyphenylsulfonyl)piperazin-1-yl)methyl]-1H-indole
EINECS	Contact for details

Quality Control

Our 3-({4-[(4-Methoxyphenyl)Sulfonyl]Piperazin-1-Yl}Methyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.