Description

2-(5-Bromothiophen-2-Yl)Pyrrolidine is a high-purity brominated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a pyrrolidine ring with a brominated thiophene moiety, enabling precise functionalization in complex molecular frameworks. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials due to the electron-rich thiophene unit.
• Chemical Biology: Employed as a molecular probe or a building block for bioconjugation in proteomics and medicinal chemistry studies.
• Catalyst Ligand Development: The pyrrolidine nitrogen can be utilized to develop novel chiral ligands for asymmetric catalysis.
• Custom Synthesis & Scale-Up: A critical starting material for contract research organizations (CROs) and custom synthesis providers serving global R&D pipelines.

Basic Information

Product Name	2-(5-Bromothiophen-2-Yl)Pyrrolidine
CAS No.	524674-43-9
Molecular Formula	C8H10BrNS
Molecular Weight	232.14 g/mol
Synonyms	2-(5-Bromothiophen-2-yl)pyrrolidine; 2-(5-Bromo-2-thienyl)pyrrolidine; Pyrrolidine, 2-(5-bromo-2-thienyl)-; 5-Bromo-2-(pyrrolidin-2-yl)thiophene; 2-(5-Bromothiophene-2-yl)pyrrolidine; 524674-43-9 (CAS); 2-(5-Bromo-thiophen-2-yl)-pyrrolidine
EINECS	Contact for details

Quality Control

Our 2-(5-Bromothiophen-2-Yl)Pyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for advanced intermediates used in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.