Description

2-Amino-4-Ethyl-5-Methyl-n-(Pyridin-3-Ylmethyl)Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within areas like kinase inhibition and targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Kinase Inhibitor Development: Serves as a key structural component in the research and synthesis of novel kinase inhibitors for oncology and inflammatory diseases.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of non-commercial, investigational compounds.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a reference standard in early-stage drug discovery.

Basic Information

Product Name	2-Amino-4-Ethyl-5-Methyl-n-(Pyridin-3-Ylmethyl)Thiophene-3-Carboxamide
CAS No.	522597-95-1
Molecular Formula	C14H17N3OS
Molecular Weight	275.37 g/mol
Synonyms	2-Amino-4-ethyl-5-methyl-N-(pyridin-3-ylmethyl)thiophene-3-carboxamide; 3-Thiophenecarboxamide, 2-amino-4-ethyl-5-methyl-N-(3-pyridinylmethyl)-; N-(Pyridin-3-ylmethyl)-2-amino-4-ethyl-5-methylthiophene-3-carboxamide; 522597-95-1; UNII-9C4J7W7Q2K; 9C4J7W7Q2K
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Ethyl-5-Methyl-n-(Pyridin-3-Ylmethyl)Thiophene-3-Carboxamide adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.