Description

2-Amino-5-Methyl-4-Phenyl-n-(Pyridin-3-Ylmethyl)Thiophene-3-Carboxamide CAS NO 522596-57-2 is a high-purity, specialized heterocyclic organic compound featuring a thiophene core substituted with amino, phenyl, and pyridinylmethyl groups. This complex molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for advanced synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Chemical Biology & Proteomics: Serves as a core structure or a derivatization handle in the design of chemical probes and enzyme inhibitors for biological pathway studies.
• Material Science Research: Potential precursor for the synthesis of advanced organic electronic materials due to its conjugated thiophene system.
• Academic & Contract Research: Essential raw material for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and medicinal chemistry programs.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects requiring this specific molecular entity for pilot or commercial-scale production.

Basic Information

Product Name	2-Amino-5-Methyl-4-Phenyl-n-(Pyridin-3-Ylmethyl)Thiophene-3-Carboxamide
CAS No.	522596-57-2
Molecular Formula	C18H17N3OS
Molecular Weight	323.41 g/mol
Synonyms	2-Amino-5-methyl-4-phenyl-N-(pyridin-3-ylmethyl)thiophene-3-carboxamide; 2-Amino-N-(3-pyridylmethyl)-5-methyl-4-phenyl-3-thiophenecarboxamide; 3-Thiophenecarboxamide, 2-amino-5-methyl-4-phenyl-N-(3-pyridinylmethyl)-; 522596-57-2; AKOS005158625; CTK8G8067; STL283910; DB-07(522596-57-2)
EINECS	Contact for details

Quality Control

Our production of 2-Amino-5-Methyl-4-Phenyl-n-(Pyridin-3-Ylmethyl)Thiophene-3-Carboxamide adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.