Description

1H-Indazole-6-Carboxamide,n-2-Azabicyclo[2.2.1]Hept-6-Yl-(9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a complex, fused bicyclic structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers seeking to develop new therapeutic agents, especially within the central nervous system (CNS) and oncology spaces. Its precise molecular architecture makes it a critical building block for creating targeted drug candidates with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: Used in the research and development of enzyme inhibitors due to its indazole-carboxamide moiety.
• Kinase Inhibitor Synthesis: A valuable building block for creating potential kinase inhibitors for oncology and inflammatory disease applications.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical entities.
• Biochemical Tool Compound: May be used to develop pharmacological probes for investigating biological pathways and target validation.

Basic Information

Item	Detail
Product Name	1H-Indazole-6-Carboxamide,n-2-Azabicyclo[2.2.1]Hept-6-Yl-(9Ci)
CAS No.	521280-03-5
Molecular Formula	C14H16N4O
Molecular Weight	256.31 g/mol
Synonyms	N-(2-Azabicyclo[2.2.1]hept-6-yl)-1H-indazole-6-carboxamide; 1H-Indazole-6-carboxamide, N-2-azabicyclo[2.2.1]hept-6-yl- (9CI); 521280-03-5; 6-Carbamoyl-1H-indazole, N-(2-azabicyclo[2.2.1]hept-6-yl) derivative; Azabicycloheptyl indazolecarboxamide; Bicyclic indazole carboxamide intermediate
EINECS	Contact for details

Quality Control

Our 1H-Indazole-6-Carboxamide,n-2-Azabicyclo[2.2.1]Hept-6-Yl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.