Description

1H-Indazole-5-Carboxamide,n-2-Azabicyclo[2.2.1]Hept-5-Yl-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization for discovering new bioactive molecules.
• CNS Drug Development: A key scaffold for research into novel therapeutics for neurological and psychiatric disorders.
• Oncology Research: Employed in the design and synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental organic chemistry and pharmacology studies.

Basic Information

Product Name	1H-Indazole-5-Carboxamide,n-2-Azabicyclo[2.2.1]Hept-5-Yl-(9Ci)
CAS No.	521279-80-1
Molecular Formula	C14H16N4O
Molecular Weight	256.31 g/mol
Synonyms	N-(2-Azabicyclo[2.2.1]hept-5-yl)-1H-indazole-5-carboxamide; 1H-Indazole-5-carboxamide, N-2-azabicyclo[2.2.1]hept-5-yl-; 521279-80-1; 2-Azabicyclo[2.2.1]hept-5-amine, N-(1H-indazol-5-ylcarbonyl)-; N-(2-Azabicyclo[2.2.1]heptan-5-yl)-1H-indazole-5-carboxamide
EINECS	Contact for details

Quality Control

Our 1H-Indazole-5-Carboxamide,n-2-Azabicyclo[2.2.1]Hept-5-Yl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP requirements. Specifications are designed to meet the stringent demands of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term stability is required. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.