Description

5-(4-Methylpiperazin-1-Ylsulfonyl)-1H-Indole is a high-purity, functionalized indole derivative featuring a methylpiperazine sulfonyl moiety. This compound is a critical pharmaceutical intermediate and research chemical used in the synthesis of novel bioactive molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Chemical Biology Probe Development: Serves as a core scaffold for creating tool compounds to study specific biological pathways and protein functions.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research projects.
• Library Synthesis: Used in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	5-(4-Methylpiperazin-1-Ylsulfonyl)-1H-Indole
CAS No.	519148-72-2
Molecular Formula	C13H17N3O2S
Molecular Weight	279.36 g/mol
Synonyms	1H-Indole, 5-[(4-methyl-1-piperazinyl)sulfonyl]-; 5-(4-Methylpiperazine-1-sulfonyl)-1H-indole; 5-(N-Methylpiperazinylsulfonyl)indole; 5-(4-Methyl-1-piperazinylsulfonyl)indole; 519148-72-2; 5-(4-Methylpiperazin-1-ylsulfonyl)indole
EINECS	Contact for details

Quality Control

Our 5-(4-Methylpiperazin-1-Ylsulfonyl)-1H-Indole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.