Description

5-[(4-Methylpiperazin-1-yl)sulfonyl]indoline is a specialized sulfonamide derivative featuring an indoline core, a key structural motif in medicinal chemistry. This compound serves as a crucial pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in drug discovery programs targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic agents.
• Chemical Reference Standard: Serves as a pure standard for analytical method development and quality control in API manufacturing.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Custom Synthesis: Starting material for the contract synthesis of more complex, target-oriented molecules for preclinical research.

Basic Information

Product Name	5-[(4-Methylpiperazin-1-yl)sulfonyl]indoline
CAS No.	519148-71-1
Molecular Formula	C13H19N3O2S
Molecular Weight	281.37 g/mol
Synonyms	1-(Indolin-5-ylsulfonyl)-4-methylpiperazine; 4-Methyl-1-(indolin-5-ylsulfonyl)piperazine; 5-[(4-Methyl-1-piperazinyl)sulfonyl]-2,3-dihydro-1H-indole; 5-(4-Methylpiperazine-1-sulfonyl)indoline; 1H-Indole, 5-[(4-methyl-1-piperazinyl)sulfonyl]-2,3-dihydro-; 519148-71-1; SCHEMBL2184241
EINECS	Contact for details

Quality Control

Our 5-[(4-Methylpiperazin-1-yl)sulfonyl]indoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.