Description

5-Chloro-3-(Thiophene-2-Carboxylhydrazidyl)-2-Oxoindoline is a specialized indoline derivative that serves as a high-value synthetic intermediate and building block in advanced organic chemistry. Its molecular architecture, featuring a chloro-substituted indolinone core linked to a thiophene carbohydrazide moiety, makes it a versatile precursor for the development of novel heterocyclic compounds. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors, where it is instrumental in the synthesis of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used as a precursor in the design and synthesis of new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Serves as a monomer or functional unit in the development of advanced organic electronic materials and specialty polymers.
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic frameworks in academic and industrial research laboratories.
• Bioconjugation & Probe Development: The reactive hydrazide group enables its use in creating fluorescent probes or bioconjugates for diagnostic applications.

Basic Information

Product Name	5-Chloro-3-(Thiophene-2-Carboxylhydrazidyl)-2-Oxoindoline
CAS No.	519147-16-1
Molecular Formula	C14H10ClN3O2S
Molecular Weight	319.76 g/mol
Synonyms	5-Chloro-3-(2-thiophenecarbohydrazido)-2-indolinone; 5-Chloro-3-[(thiophene-2-carbonyl)hydrazinylidene]indolin-2-one; 2-Oxo-5-chloro-3-(thiophene-2-carboxylhydrazinyl)indoline; 1H-Indol-2-one, 5-chloro-3-[(2-thienylcarbonyl)hydrazinylidene]-; 519147-16-1; Thiophene carbohydrazide indoline derivative
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-(Thiophene-2-Carboxylhydrazidyl)-2-Oxoindoline is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.