Description

Ethyl 3-Amino-4-(Methylsulfonyl)-5-(Methylthio)Thiophene-2-Carboxylate is a high-purity, multi-functional thiophene derivative serving as a critical advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring both methylsulfonyl and methylthio substituents on the thiophene core, makes it an indispensable building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the design and synthesis of new-generation herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a monomer or building block for creating conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments due to the electron-rich thiophene scaffold.
• Academic & Contract Research: A valuable reagent for methodological development and exploration of new heterocyclic chemistry in university and CRO laboratories.
• Custom Synthesis: Acts as a starting material for the contract manufacturing of complex, bespoke molecules for various industrial applications.

Basic Information

Product Name	Ethyl 3-Amino-4-(Methylsulfonyl)-5-(Methylthio)Thiophene-2-Carboxylate
CAS No.	519056-53-2
Molecular Formula	C9H13NO4S3
Molecular Weight	295.39 g/mol
Synonyms	Ethyl 3-Amino-4-(methylsulfonyl)-5-(methylthio)thiophene-2-carboxylate; 3-Amino-4-(methylsulfonyl)-5-(methylthio)thiophene-2-carboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 3-amino-4-(methylsulfonyl)-5-(methylthio)-, ethyl ester; Ethyl 3-amino-4-methanesulfonyl-5-methylsulfanylthiophene-2-carboxylate; 519056-53-2; AMTTC; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Amino-4-(Methylsulfonyl)-5-(Methylthio)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.