Description

2-Thiophenesulfonamide,5-Cyano-(9Ci) is a high-purity, specialized heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a cyano-substituted thiophene core with a sulfonamide functional group, enabling precise molecular design. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where the thiophene-sulfonamide motif acts as a key pharmacophore.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a monomer or functional additive in the creation of advanced polymers and organic electronic materials due to its conjugated system.
• Chemical Biology Probe Development: Employed in designing selective enzyme inhibitors and molecular probes for biochemical pathway analysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	2-Thiophenesulfonamide,5-Cyano-(9Ci)
CAS No.	519055-65-3
Molecular Formula	C5H4N2O2S2
Molecular Weight	188.23 g/mol
Synonyms	5-Cyanothiophene-2-sulfonamide; 2-Cyano-5-sulfamoylthiophene; 5-Cyano-2-thiophenesulfonamide; Thiophene-2-sulfonamide, 5-cyano-; 5-Cyanothiophene-2-sulfonic acid amide; 2-Thiophenesulfonamide, 5-cyano- (9CI); 5-Cyano-thiophene-2-sulfonic acid amide
EINECS	Contact for details

Quality Control

Our 2-Thiophenesulfonamide,5-Cyano-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with batch-specific data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.