Description

3-Aminomethyl-5-Fluoro-1,3-Dihydro-Indol-2-One is a high-purity, fluorinated indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical agents, particularly in the research of central nervous system (CNS) and oncological therapeutics. It is essential for medicinal chemists and R&D departments in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new molecular entities with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• API Synthesis: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Development: The aminomethyl group allows for functionalization, making it useful for creating biochemical probes and labeled compounds.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic and pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	3-Aminomethyl-5-Fluoro-1,3-Dihydro-Indol-2-One
CAS No.	518066-41-6
Molecular Formula	C9H9FN2O
Molecular Weight	180.18 g/mol
Synonyms	5-Fluoro-3-(aminomethyl)indolin-2-one; 3-(Aminomethyl)-5-fluoro-2-indolinone; 5-Fluoro-3-aminomethyloxindole; 3-Aminomethyl-5-fluorooxindole; 5-Fluoro-3-(aminomethyl)-1,3-dihydro-2H-indol-2-one; 518066-41-6; 3-Aminomethyl-5-fluoroindolin-2-one
EINECS	Contact for details

Quality Control

Our 3-Aminomethyl-5-Fluoro-1,3-Dihydro-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.