Description

Cyclopentanone, 3-(Phenylthio)-, (3S)- (9Ci) CAS NO 518028-03-0 is a high-purity chiral building block characterized by its cyclopentanone core functionalized with a phenylthio group at the 3-position in the (S)-configuration. This compound matters as a versatile and stereochemically defined intermediate for the synthesis of complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the construction of novel, stereoselective herbicides, fungicides, or plant growth regulators where the specific spatial orientation of the molecule is critical for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in transition metal catalysis to induce enantioselectivity in chemical reactions.
• Fine Chemical & Specialty Polymer Building Block: Employed in the production of advanced materials, liquid crystals, or specialty polymers requiring specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for chemists in university and corporate research laboratories exploring new synthetic methodologies and structure-activity relationships (SAR).
• Flavor & Fragrance Intermediate: Potential use in the synthesis of complex odorants or flavoring agents where the sulfur-containing moiety contributes to unique sensory profiles.

Basic Information

Product Name	Cyclopentanone, 3-(Phenylthio)-, (3S)- (9Ci)
CAS No.	518028-03-0
Molecular Formula	C11H12OS
Molecular Weight	192.28 g/mol
Synonyms	(3S)-3-(Phenylthio)cyclopentanone; (S)-3-(Phenylthio)cyclopentanone; 3-(Phenylthio)cyclopentanone, (3S)-; 3-Phenylsulfanylcyclopentanone, (3S)-; (S)-3-Phenylthiocyclopentanone; 518028-03-0; (3S)-3-(Phenylsulfanyl)cyclopentanone
EINECS	Contact for details

Quality Control

Our Cyclopentanone, 3-(Phenylthio)-, (3S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.