Description

(E)-3-(1H-Benzo[D]Imidazol-1-Yl)-2-Methyl-n-(2-Oxoindolin-3-Ylidene)Propanehydrazide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially those targeting specific enzyme pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly those with indolinone and benzimidazole pharmacophores.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening (HTS) for drug discovery programs.
• Biochemical Probe Development: Serves as a starting material for creating specialized probes to study enzyme inhibition and receptor-ligand interactions.
• Organic Synthesis Reference Standard: Employed as a pure reference compound for analytical method development and validation in QC laboratories.
• Academic Research: Utilized in university and institutional research for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	(E)-3-(1H-Benzo[D]Imidazol-1-Yl)-2-Methyl-n-(2-Oxoindolin-3-Ylidene)Propanehydrazide
CAS No.	518018-85-4
Molecular Formula	C20H18N6O2
Molecular Weight	374.40 g/mol
Synonyms	(E)-3-(1H-Benzoimidazol-1-yl)-2-methyl-N-(2-oxoindolin-3-ylidene)propanehydrazide; (E)-3-(1H-Benzoimidazol-1-yl)-2-methyl-N-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanehydrazide; (E)-3-(1H-Benzoimidazol-1-yl)-2-methyl-N-(2-oxoindolin-3-ylidene)propanehydrazide; 3-(1H-Benzoimidazol-1-yl)-2-methyl-N-(2-oxoindolin-3-ylidene)propanehydrazide; (E)-3-(1H-Benzoimidazol-1-yl)-2-methyl-N-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)propanehydrazide; CAS 518018-85-4; Propanehydrazide, 3-(1H-benzimidazol-1-yl)-2-methyl-N-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-, (E)-
EINECS	Contact for details

Quality Control

Our production of (E)-3-(1H-Benzo[D]Imidazol-1-Yl)-2-Methyl-n-(2-Oxoindolin-3-Ylidene)Propanehydrazide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all test results are provided and available upon request. Our quality systems are designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.