Description

1-(Benzyloxy)-4-Iodo-2-Methylbenzene is a high-purity, functionalized aromatic compound characterized by its benzyl-protected phenol and iodine substituent, making it a versatile building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the iodine atom facilitates further cross-coupling reactions.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis, such as palladium-catalyzed coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers due to its aromatic and halogen functionalities.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.

Basic Information

Product Name	1-(Benzyloxy)-4-Iodo-2-Methylbenzene
CAS No.	516521-49-6
Molecular Formula	C14H13IO
Molecular Weight	324.16 g/mol
Synonyms	4-Iodo-2-methylphenyl benzyl ether; 2-Methyl-4-iodophenyl benzyl ether; 1-Benzyloxy-4-iodo-2-methylbenzene; Benzyl 4-iodo-2-methylphenyl ether; 4-Iodo-o-cresol benzyl ether; (4-Iodo-2-methylphenoxy)methyl]benzene; 1-Iodo-4-(benzyloxy)-3-methylbenzene
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxy)-4-Iodo-2-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.