Description

Ethyl 2-[(Cyanoacetyl)Amino]-5-Isopropylthiophene-3-Carboxylate is a high-value, multi-functional heterocyclic building block featuring a thiophene core substituted with cyanoacetyl and isopropyl groups. This compound matters as a critical synthetic intermediate, enabling the construction of complex molecular architectures for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its thiophene scaffold for bioactivity.
• Organic Electronic Materials: Acts as a building block for π-conjugated systems in the development of organic semiconductors, OLEDs, and sensors due to its electron-withdrawing cyanoacetyl group.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color fastness and specific light-absorption properties.
• Ligand and Catalyst Development: Useful for creating novel ligands for metal catalysis or as a scaffold for organocatalysts in asymmetric synthesis.
• Polymer Modification: Incorporated as a functional monomer to impart specific chemical or physical properties to advanced polymeric materials.

Basic Information

Product Name	Ethyl 2-[(Cyanoacetyl)Amino]-5-Isopropylthiophene-3-Carboxylate
CAS No.	515861-07-1
Molecular Formula	C13H16N2O3S
Molecular Weight	280.34 g/mol
Synonyms	Ethyl 2-[(cyanoacetyl)amino]-5-(propan-2-yl)thiophene-3-carboxylate; 2-[(Cyanoacetyl)amino]-5-isopropylthiophene-3-carboxylic acid ethyl ester; 5-Isopropyl-2-[(cyanoacetylamino)]thiophene-3-carboxylic acid ethyl ester; Thiophene-3-carboxylic acid, 2-[(cyanoacetyl)amino]-5-(1-methylethyl)-, ethyl ester; CAS 515861-07-1
EINECS	Contact for details

Quality Control

Our Ethyl 2-[(Cyanoacetyl)Amino]-5-Isopropylthiophene-3-Carboxylate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations for chemical products.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.