Description

1H-Indole-3-Propanoic Acid, Alpha(1,1-Dioxido-2(3H)-Isothiazolyl)-1, Methyl Ester, (Alphas) is a specialized synthetic intermediate of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines indole and isothiazolidine dioxide moieties, making it a versatile building block for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or anti-inflammatory pathways.
• Agrochemical Research: Used in developing new generations of pesticides and herbicides, leveraging its complex heterocyclic structure for bioactivity.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Advanced Material Synthesis: Acts as a building block for creating specialized polymers or organic electronic materials with unique properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis projects and library generation for high-throughput screening.

Basic Information

Product Name	1H-Indole-3-Propanoic Acid, Alpha(1,1-Dioxido-2(3H)-Isothiazolyl)-1, Methyl Ester, (Alphas)
CAS No.	515130-15-1
Molecular Formula	C15H16N2O4S
Molecular Weight	320.36 g/mol
Synonyms	Methyl 3-[1-(1,1-dioxo-1,2-thiazolidin-2-yl)-1H-indol-3-yl]propanoate; (Alphas)-Methyl α-(1,1-dioxido-2(3H)-isothiazolyl)-1H-indole-3-propanoate; 515130-15-1; 1H-Indole-3-propanoic acid, α-(1,1-dioxido-2(3H)-isothiazolyl)-, methyl ester; Methyl 3-(1-(1,1-dioxido-2,3-dihydroisothiazol-2-yl)-1H-indol-3-yl)propanoate
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Propanoic Acid, Alpha(1,1-Dioxido-2(3H)-Isothiazolyl)-1, Methyl Ester, (Alphas) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.