Description

Dimethyl 5-[(Cyanoacetyl)Amino]-3-Methylthiophene-2,4-Dicarboxylate is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its molecular architecture, featuring a thiophene core with ester, cyano, and amide functionalities, makes it a versatile synthon for constructing complex molecules in medicinal chemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients. Its CAS number is 514219-45-5.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial R&D.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional materials due to its conjugated thiophene system.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized colorants and imaging agents.

Basic Information

Product Name	Dimethyl 5-[(Cyanoacetyl)Amino]-3-Methylthiophene-2,4-Dicarboxylate
CAS No.	514219-45-5
Molecular Formula	C₁₂H₁₂N₂O₅S
Molecular Weight	296.30 g/mol
Synonyms	5-[(Cyanoacetyl)amino]-3-methylthiophene-2,4-dicarboxylic acid dimethyl ester; Dimethyl 5-(2-cyanoacetamido)-3-methylthiophene-2,4-dicarboxylate; 3-Methyl-5-[(cyanoacetyl)amino]thiophene-2,4-dicarboxylic Acid Dimethyl Ester; 2,4-Thiophenedicarboxylic acid, 5-[(cyanoacetyl)amino]-3-methyl-, dimethyl ester; CAS 514219-45-5
EINECS	Contact for details

Quality Control

Our Dimethyl 5-[(Cyanoacetyl)Amino]-3-Methylthiophene-2,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.